In health care, we talk a lot about evidence-based practice or its younger brother, evidence-informed practice. Aligned with this, we have developed what is now known as the three-legged stool of evidence-based practice. The now-legendary three legs of the proverbial stool include research evidence, clinical expertise, and patients' values, needs, and preferences. However, what has been forgotten in this whole construct is that any good stool is useless unless it stands upon a sound foundation, or as Newton would have it, “standing on the shoulders of giants”. Let’s call them the Three Amigos.

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